Online Formulary
  • Using the Formulary
  • Therapeutic Sections
    • 1. Gastro-intestinal system
    • 2. Cardiovascular system
    • 3. Respiratory
    • 4. Nervous system
    • 5. Infection
    • 6. Endocrine system
    • 7. Genito-urinary system
    • 8. Immune System
    • 8. Malignant disease
    • 9. Blood and blood-forming organs
    • 9. Nutrition and metabolic disorders
    • 10. Musculoskeletal system
    • 11. Eye
    • 12. Ear
    • 12. Nose
    • 12. Oropharynx
    • 13. Skin
    • 14. Vaccines
    • 15. Anaesthesia
    • 16. Emergency Treatment of Poisoning
    • Palliative Care
    • Wound management products
    • Stoma products
    • Continence products
    • Borderline substances
    • General recommendations and information
    • Shared Care
  • Using the Formulary
  • Therapeutic Sections
    • 1. Gastro-intestinal system
      • 1.1 Chronic bowel disorders
      • 1.2 Constipation and bowel cleansing
        • 1.2.1 Bowel cleansing
        • 1.2.2 Constipation
          • 1.2.2.2 Osmotic Laxatives
          • 1.2.2.3 Selective 5HT4-receptor agonists
          • 1.2.2.5 Stimulant Laxatives
          • 1.2.2.6 Opioid receptor antagonists
      • 1.3 Diarrhoea
      • 1.4 Disorders of gastric acid and ulceration
      • 1.5 Food allergy
      • 1.6 Gastro-intestinal smooth muscle spasm
      • 1.7 Liver disorders and related conditions
      • 1.8 Obesity
      • 1.9 Rectal and anal disorders
      • 1.10 Reduced exocrine secretions
      • 1.11 Stoma care
      • 1.12 Eosinophilic Oesophagitis
      • Local recommendations (Gastro-intestinal)
    • 2. Cardiovascular system
    • 3. Respiratory
    • 4. Nervous system
    • 5. Infection
    • 6. Endocrine system
    • 7. Genito-urinary system
    • 8. Immune System
    • 8. Malignant disease
    • 9. Blood and blood-forming organs
    • 9. Nutrition and metabolic disorders
    • 10. Musculoskeletal system
    • 11. Eye
    • 12. Ear
    • 12. Nose
    • 12. Oropharynx
    • 13. Skin
    • 14. Vaccines
    • 15. Anaesthesia
    • 16. Emergency Treatment of Poisoning
    • Palliative Care
    • Wound management products
    • Stoma products
    • Continence products
    • Borderline substances
    • General recommendations and information
    • Shared Care
  • Search
  • Feedback

Drug Status Key

  • On Formulary
  • Specialist Initiation

    On formulary but requires initiation by a specialist. 
    GPs may then take on maintenance prescribing - 
    Using the Formulary (eastkentformulary.nhs.uk)

  • Shared Care
  • Hospital Only
  • Not Recommended

Preferences

  • First Line
  • Second Line
  • Third Line
  • No Preference

1.2.2.2 Osmotic Laxatives

Expand All / Expand All (incl. cost)

Lactulose

NICE EMC

Lactulose 3.1-3.7g/5ml oral solution

Pack Price
1000 ml
200 ml
2000 ml
300 ml
500 ml £4.92

Macrogol

NICE EMC SPS

Macrogol compound half-strength oral powder sachets NPF sugar free (Cost effective option: CosmoCol Half)

Pack Price
20 sachet
30 sachet £4.38

Macrogol compound oral powder sachets NPF sugar free (Cost effective option: CosmoCol)

Pack Price
20 sachet £4.18
30 sachet £5.97
4 sachet
50 sachet
8 sachet

Phosphate enema

NICE EMC

Phosphates enema (Formula B) 128ml standard tube

Pack Price
1 enema £55.46

Phosphates enema (Formula B) 128ml long tube

Pack Price
1 enema £75.40

Online Formulary by M.O.M. Systems

NICE guidance is available from https://www.nice.org.uk/guidance All rights reserved. Subject to Notice of rights.
NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.

© Copyright 2025