1.2.2.6 Opioid receptor antagonists

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Naldemedine is recommended as an option for treating opioid induced constipation in adults whose constipation has not adequately responded to laxatives. An inadequate response is defined as opioid-induced constipation symptoms of at least moderate severity in at least 1 of the 4 stool symptom domains (that is, incomplete bowel movement, hard stools, straining or false alarms) while taking at least 1 laxative class for at least 4 days during the prior 2 weeks.

For full details please see NICE TA 651  https://www.nice.org.uk/guidance/ta651

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30 tablet £55.20