4.1.2.1 NMDA Receptor Antagonists

For people with an established diagnosis of Alzheimer’s disease who are already taking an AChEI, if additional therapy is required, GPs may start treatment with memantine if confident to do so on the advice of a specialist/clinician (Nurse, Consultant, Community Geriatrician, KMPT specialists, GPs with a specialist knowledge) who has the necessary knowledge and skills and does not require ongoing specialist monitoring.

Memantine monotherapy should be initiated or recommended by a specialist.