Drug Status Key

Preferences

  • First Line
  • Second Line
  • Third Line
  • No Preference

6.3.1.3 Dipeptidylpeptidase-4 inhibitors (gliptins)

Position Statement: DPP-4 inhibitors (gliptins) in the management of Type 2 Diabetes

Sitagliptin is the first line/preferred cost-effective gliptin. Sitagliptin is first line for all eligible patients/new initiations. Where existing patients are prescribed a different gliptin, and ongoing prescribing of a gliptin is indicated following diabetes review, switch to generic sitagliptin if appropriate.

Linagliptin is the second line gliptin to be used only after sitagliptin has been tried, or if eGFR <45ml/min/1.73m2.

Expand All / Expand All (incl. cost)

Sitagliptin is the first line/preferred cost-effective gliptin. Sitagliptin is first line for all eligible patients/new initiations. Where existing patients are prescribed a different gliptin, and ongoing prescribing of a gliptin is indicated following diabetes review, switch to generic sitagliptin if appropriate.

Pack Price
28 tablet £3.06
Pack Price
28 tablet £3.52
Pack Price
100 tablet
28 tablet £3.66

Sitagliptin is the first line/preferred gliptin. Linagliptin is the second line gliptin to be used only after sitagliptin has been tried, or if eGFR <45ml/min/1.73m2.

Pack Price
28 tablet £33.26
30 tablet

Sitagliptin is the first line/preferred cost-effective gliptin. Where existing patients are prescribed alogliptin, and ongoing prescribing of a gliptin is indicated following next diabetes review, switch to generic sitagliptin if appropriate.

Pack Price
28 tablet £26.60
Pack Price
28 tablet £26.60
Pack Price
28 tablet £26.60
Pack Price
28 tablet £31.60
Pack Price
28 tablet £31.60
Pack Price
56 tablet £28.57
60 tablet