4.6.1.2 Opioids

Please see opioid safety resources under Local Recommendations (Nervous System) – Pain (here).

These include:

  • KMCCG Lidocaine plaster position statement
  • Opioid Tapering Resource Pack
  • KMCCG Opioid Position Statement on Opioid Prescribing
  • KM Controlled Drugs Benzo Treatment Agreement
  • Kent and Medway Guidance to Support the Safe and Effective, Initiation and Review of Opioids
  • Information leaflet – 10 opioid safety messages
  • Kent and Medway Position Statement: Safe Prescribing of Injectable Medicines in Primary Care
  • Morphine Liquid Appropriate Use Guidance
  • Prescribing Liquid Morphine Position Statement

Expand All / Expand All (incl. cost)

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
2 patch
4 patch £17.60

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
4 patch £31.55

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
4 patch £49.15

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
4 patch £57.46

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
3 patch
4 patch £15.80
5 patch
6 patch

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
3 patch
4 patch £23.71
5 patch
6 patch

Butec patches are the most cost effective preparation for this strengthControlled drugs should be prescribed by brand Buprenorphine patches should be
prescribed in accordance with the Chronic Pain Guidelines: http://tinyurl.com/znwuw7f

Pack Price
3 patch
4 patch £31.60
5 patch
6 patch

On formulary only for use as strong analgesic for the relief of moderate to severe pain NOT for opioid substitution

Pack Price
50 tablet £5.04

On formulary only for use as strong analgesic for the relief of moderate to severe pain NOT for opioid substitution

Pack Price
50 tablet £10.07
7 tablet £1.36

DO NOT PRESCRIBE. All services are commissioned through Turning Point and patients should be referred back to Turning Point to obtain supplies to
ensure this is only supplied with the required behavioural support. In the event of a request for an emergency supply. DO NOT PRESCRIBE. All patients
are notified that Turning Point can be contacted 24/7 to discuss and, if appropriate, obtain an additional prescription. Other substance abuse services will
have a similar arrangement. Contact details for Turning Point are Referrals (24/7 Helpline) Advice: 0300 123 1186.

Pack Price
7 tablet £1.44

DO NOT PRESCRIBE. All services are commissioned through Turning Point and patients should be referred back to Turning Point to obtain supplies to
ensure this is only supplied with the required behavioural support. In the event of a request for an emergency supply. DO NOT PRESCRIBE. All patients
are notified that Turning Point can be contacted 24/7 to discuss and, if appropriate, obtain an additional prescription. Other substance abuse services will
have a similar arrangement. Contact details for Turning Point are Referrals (24/7 Helpline) Advice: 0300 123 1186.

Pack Price
7 tablet £4.32

DO NOT PRESCRIBE unless you are one of the very few practices in East Kent which have a contract for Opioid substitution therapy services. All
services are commissioned through Turning Point and patients should be referred back to Turning Point to obtain supplies to ensure this is only supplied with the required behavioural support .In the event of a request for an emergency supply. DO NOT PRESCRIBE. All patients are notified that Turning Point can be contacted 24/7 to discuss and if appropriate, obtain an additional prescription. Other substance abuse services will have a similar arrangement.Contact details for Turning Point are Referrals, 24/7 Helpline, Advice 0300 123 1186

Pack Price
28 tablet £25.40

DO NOT PRESCRIBE unless you are one of the very few practices in East Kent which have a contract for Opioid substitution therapy services. All
services are commissioned through Turning Point and patients should be referred back to Turning Point to obtain supplies to ensure this is only supplied with the required behavioural support .In the event of a request for an emergency supply. DO NOT PRESCRIBE. All patients are notified that Turning Point can be contacted 24/7 to discuss and if appropriate, obtain an additional prescription. Other substance abuse services will have a similar arrangement.Contact details for Turning Point are Referrals, 24/7 Helpline, Advice 0300 123 1186

Pack Price
28 tablet £76.19
Pack Price
5 ampoule
Pack Price
100 tablet £3.27
1000 tablet
12 tablet
16 tablet
24 tablet
30 tablet £0.98
32 tablet
4 tablet
48 tablet
50 tablet
500 tablet
8 tablet
Pack Price
100 tablet £9.03
12 tablet
24 tablet
32 tablet £2.89
60 tablet

Prescribe generically

Pack Price
100 tablet £9.28
30 tablet
32 tablet £2.97
90 tablet

prescribing as zapain is more cost effective

Pack Price
100 tablet £3.80
30 tablet £1.14
500 tablet

prescribing as zapain is more cost effective

Pack Price
100 capsule £3.96
24 capsule
30 capsule
8 capsule

Prescribe generically.Capsules should be reserved for patients who cannot swallow tablets. Tablets are more cost effective.

Pack Price
10 capsule
100 capsule £27.78
20 capsule
24 capsule
32 capsule £8.89
Pack Price
100 tablet £2.54

Limited evidence base to support this dose of codeine

Pack Price
100 capsule £7.25

Limited evidence base to support this dose of codeine

Pack Price
100 tablet £8.25
Pack Price
100 tablet £6.53
30 tablet £1.96
500 tablet
Pack Price
100 tablet £2.75
28 tablet £0.77
30 tablet
500 tablet
Pack Price
100 tablet £3.82
28 tablet £1.07
30 tablet
500 tablet
Pack Price
100 tablet
28 tablet £1.91
30 tablet
Pack Price
500 ml £6.64
Pack Price
10 ampoule

Mezolar or Matrifen are most cost effective preparations. Prescribe by brand in line with recommendations for Controlled Drugs

Pack Price
5 patch £12.59

Mezolar or Matrifen are most cost effective preparations. Prescribe by brand in line with recommendations for Controlled Drugs

Pack Price
5 patch £17.99
Pack Price
5 patch £15.46

Mezolar or Matrifen are most cost effective preparations. Prescribe by brand in line with recommendations for Controlled Drugs

Pack Price
5 patch £33.66

Mezolar or Matrifen are most cost effective preparations. Prescribe by brand in line with recommendations for Controlled Drugs

Pack Price
5 patch £46.99

Mezolar or Matrifen are most cost effective preparations. Prescribe by brand in line with recommendations for Controlled Drugs

Pack Price
5 patch £57.86

Hospice recommendation only. (Updated: January 2015)

Pack Price
28 tablet £139.72
4 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
28 tablet £139.72
4 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
28 tablet £139.72
4 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
28 tablet £139.72
4 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
28 tablet £139.72
4 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 tablet £49.99
30 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 tablet £49.99
30 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 tablet £49.99
30 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 tablet £49.99
30 tablet

Hospice recommendation only. (Updated: January 2015)

Pack Price
30 tablet £149.70

Hospice recommendation only. (Updated: January 2015)

Pack Price
30 tablet £149.70

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 dose
20 dose
6 dose

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 dose
20 dose
32 dose £145.92
6 dose
8 dose £36.48

Hospice recommendation only. (Updated: January 2015)

Pack Price
10 dose
20 dose
6 dose

Hospice recommendation only. (Updated: January 2015)

Pack Price
32 dose £145.92
8 dose £36.48

Hospice recommendation only. (Updated: January 2015)

Pack Price
3 lozenge £21.05
30 lozenge £210.41

Hospice recommendation only. (Updated: January 2015)

Pack Price
3 lozenge £21.05
30 lozenge £210.41

Hospice recommendation only. (Updated: January 2015)

Pack Price
3 lozenge £21.05
30 lozenge £210.41

Hospice recommendation only. (Updated: January 2015)

Pack Price
3 lozenge £21.05
30 lozenge £210.41

Hospice recommendation only. (Updated: January 2015)

Pack Price
3 lozenge £21.05
30 lozenge £210.41

Hospice recommendation only. (Updated: January 2015)

Pack Price
3 lozenge £16.80
30 lozenge £210.41
Pack Price
56 tablet (8 x 7 tablets) £2.00
Pack Price
56 tablet (8 x 7 tablets) £2.50
Pack Price
56 tablet (8 x 7 tablets) £3.50
Pack Price
56 tablet (8 x 7 tablets) £4.75
Pack Price
56 tablet (8 x 7 tablets) £9.50
Pack Price
56 tablet (8 x 7 tablets) £13.00

Consider using Sevredol for use in chronic pain in place of Oramorph. Controlled drugs should be prescribed by brand

Pack Price
56 tablet £5.31

Consider using Sevredol for use in chronic pain in place of Oramorph. Controlled drugs should be prescribed by brand

Pack Price
56 tablet £10.61

Consider using Sevredol for use in chronic pain in place of Oramorph. Controlled drugs should be prescribed by brand

Pack Price
56 tablet £28.02
Pack Price
60 tablet £3.29
Pack Price
60 tablet £9.10

Zomorph is the most cost effective preparation for 12 hour modified release morphine capsules. Controlled drugs should be prescribed by brand

Pack Price
60 capsule £3.47

Zomorph is the most cost effective preparation for 12 hour modified release morphine capsules. Controlled drugs should be prescribed by brand

Pack Price
28 capsule
60 capsule £8.30

Zomorph is the most cost effective preparation for 12 hour modified release morphine capsules. Controlled drugs should be prescribed by brand

Pack Price
28 capsule
60 capsule £16.20

Zomorph is the most cost effective preparation for 12 hour modified release morphine capsules. Controlled drugs should be prescribed by brand

Pack Price
60 capsule £21.80

Zomorph is the most cost effective preparation for 12 hour modified release morphine capsules. Controlled drugs should be prescribed by brand

Pack Price
28 capsule
60 capsule £43.60
Pack Price
1 suppository
12 suppository
Pack Price
10 ampoule £7.45
5 ampoule
Pack Price
10 ampoule £254.73
Pack Price
10 ampoule £48.44
5 ampoule
Pack Price
5 ampoule £12.00

For use for breakthrough pain in chronic pain consider immediate release morphine (Sevredol) in place of Oramorph.

Pack Price
100 ml
300 ml £3.76
500 ml

CONCENTRATED SOLUTION

Pack Price
120 ml £19.50
30 ml

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
60 tablet £5.20

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
60 tablet £12.47

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
60 tablet £24.32

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
60 tablet £38.50

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
60 tablet £81.34
Pack Price
10 ampoule
5 ampoule
Pack Price
10 ampoule
5 ampoule

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
30 sachet

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
30 sachet

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
30 sachet

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
30 sachet

Zomorph is the most cost effective preparation for 12 hour modified release morphine although a capsule form rather than a sachet. Controlled drugs should
be prescribed by brand

Pack Price
30 sachet

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 capsule £11.43

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 capsule £22.86

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 capsule £45.71

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
28 tablet £12.52

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
28 tablet
56 tablet £25.04

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 tablet £38.12

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
28 tablet
56 tablet £50.08

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 tablet £76.23

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
28 tablet
56 tablet £100.19

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 tablet £152.49

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.
MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
28 tablet
56 tablet £200.39

Oxycodone and morphine sulfate have a similar safety and efficacy profile, however morphine sulfate is significantly less costly than oxycodone.

MORPHINE sulphate should therefore be considered first line where strong opioids are required.

Pack Price
56 tablet £305.02
Pack Price
1 ml
Pack Price
250 ml £8.81
Pack Price
120 ml £46.63

Targinact is not recommended as the clinical benefit in patients receiving regular laxative therapy is uncertain and the economic case for use was not proven (in line with the Scottish Medicines Consortium advice June 2009) (Updated: July 2015)

Pack Price
28 tablet £21.16

Targinact is not recommended as the clinical benefit in patients receiving regular laxative therapy is uncertain and the economic case for use was not proven (in line with the Scottish Medicines Consortium advice June 2009) (Updated: July 2015)

Pack Price
56 tablet £42.32

Targinact is not recommended as the clinical benefit in patients receiving regular laxative therapy is uncertain and the economic case for use was not proven (in line with the Scottish Medicines Consortium advice June 2009) (Updated: July 2015)

Pack Price
56 tablet £84.62

Targinact is not recommended as the clinical benefit in patients receiving regular laxative therapy is uncertain and the economic case for use was not proven (in line with the Scottish Medicines Consortium advice June 2009) (Updated: July 2015)

Pack Price
56 tablet £169.28

Preferred brand where Tramadol is indicated

Pack Price
30 tablet
60 tablet

Preferred brand where Tramadol is indicated

Pack Price
28 tablet
30 tablet
60 tablet

Preferred brand where Tramadol is indicated

Pack Price
28 tablet
30 tablet
60 tablet
Pack Price
60 tablet £4.60
Pack Price
100 tablet £13.33
20 tablet
Pack Price
100 capsule £2.50
105 capsule
140 capsule
30 capsule £0.75
Pack Price
60 capsule £7.24

Tramacet not recommended due to sub-therapeutic dose of paracetamol

Pack Price
20 tablet
60 tablet £5.71
Pack Price
100 tablet
60 tablet £7.12
Pack Price
20 sachet
60 sachet
Pack Price
60 sachet
Pack Price
10 ampoule
5 ampoule £4.00

Specialist initiation where morphine and/or oxycodone have failed to provide adequate pain control; or have been tried and not tolerated’

Pack Price
28 tablet £12.46
56 tablet £24.91

Specialist initiation where morphine and/or oxycodone have failed to provide adequate pain control; or have been tried and not tolerated’

Pack Price
56 tablet £49.82

Specialist initiation where morphine and/or oxycodone have failed to provide adequate pain control; or have been tried and not tolerated’

Pack Price
56 tablet £74.73

Specialist initiation where morphine and/or oxycodone have failed to provide adequate pain control; or have been tried and not tolerated’

Pack Price
56 tablet £99.64

Specialist initiation where morphine and/or oxycodone have failed to provide adequate pain control; or have been tried and not tolerated’

Pack Price
56 tablet £124.55
Pack Price
1 tablet
100 tablet £287.48
30 tablet
Pack Price
1 ml
Pack Price
100 tablet £7.86
28 tablet £2.20
30 tablet
500 tablet
Pack Price
100 tablet
Pack Price
56 tablet £5.20
Pack Price
56 tablet £8.66
Pack Price
56 tablet £10.95
Pack Price
150 ml

Not on EKHUFT formualry

Pack Price
112 tablet £22.11
Pack Price
100 tablet
28 tablet £27.33
Pack Price
100 capsule
28 capsule £28.50
Pack Price
10 ampoule